Latest Research
New blood test aims to detect aggressive prostate cancer earlier
Research Institute - McGill University Health Centre
By identifying cancer-specific methylation signals in blood, researchers from the Research Institute of the McGill University Health Centre hope to enable safer, earlier detection of high-risk prostate cancer.
Prostate Cancer Survivorship Experience: Patient Reported Outcome Measures and Focus Group Results
Academia
There are an ever increasing number of prostate cancer survivors. These patents are currently followed up in secondary care. Focus of care is on recurrence and acute management, not holistic care.
ProsCan for Men: Randomized controlled trial of a decision support intervention for men with localized prostate cancer
Academia
This paper presents the design of a randomised controlled trial of a decision support/psychosocial intervention for men newly diagnosed with localised prostate cancer.
Telomere shortening caused by poor environments could lead to increased prostate cancer risk
Black Enterprise
The stress of poverty has long been associated with shortened telomeres, and a 2013 study indicated that these shortened telomeres had a negative effect on the health outcomes of chronically poor people. Now, new research indicates that these poor health outcomes could also explain poor prostate health. - Published July 17th 2024
Relugolix now available in Canada for advanced prostate cancer
Urology Times
"Lowering the body's testosterone level is a first-line treatment approach for men with advanced prostate cancer. Now, physicians in Canada have a once-daily oral GnRH antagonist treatment option in their armamentarium that helps men with advanced prostate cancer by lowering testosterone levels without leading to testosterone flares" - Published March 13th 2024
Choosing Health, Choosing Treatment: Patient Choice After Diagnosis of Localized Prostate Cancer
Academia
Implementing patient choice in the domain localized prostate cancer is not going to be without difficulties. For example, medical expertise underlies the development of trust in patient-physician communication for men with cancer, which may mean that patients will still expect health professionals to use their medical expertise to decide upon the best course of action. - Published in 2009
Evaluation of a multidisciplinary allied health prostate cancer clinic
Academia
Prostate cancer is the most common male cancer, with increasingly longer survival, and many treatment options for advanced disease. Men with prostate cancer report a high level of unmet supportive care needs. To evaluate unmet needs of a small cohort of Australian men with advanced prostate cancer, and their partners, and to assess the impact of attendance at a multidisciplinary allied health clinic on meeting these needs. - Published in 2017
Aiming for a holistic integrated service for men diagnosed with prostate cancer – Definitions of standards and skill sets for nurses and allied healthcare professionals
Academia
Specialist nurses and allied healthcare professionals play a vital role alongside urologists and oncologists to provide care to men with prostate cancer and their families. -We present a set of standards and consensus recommendations for the roles and skill-set required for these practitioners to provide gold-standard prostate cancer care. -These recommendations could form the basis for development of comprehensive integrated prostate cancer pathways in prostate cancer centres as well as providing guidance for any units treating men with prostate cancer. - Published in 2016
The value of prostate cancer support groups: a pilot study of primary physicians’ perspectives
Academia
In Canada, prostate cancer (PCa) is the most common male cancer, and prostate cancer support groups (PCSGs) have prevailed for more than 20 years providing support to men with PCa and their families. While the format, focus and benefits of attending PCSGs have been reported little is known about primary physicians’ (PPs) perceptions of these groups. This article describes Canadian primary physicians’ views about face-to-face and web-based PCSGs. - Published in 2014
Prostate Cancer Survivors: Physical, Emotional and Practical Concerns from the LIVESTRONG survey
Academia
To determine whether a relationship exists between types of treatment received and/or survivorship status of prostate cancer survivors with physical, emotional, and practical concerns that they experience with the hypothesis that no such relationship exists. - Published in 2016
Do men with prostate cancer and their partners receive the information they need for optimal illness self-management in the immediate post-diagnostic phase?
Academia
Prostate cancer is the most common cancer in Australian men, and approximately 92% of the patients survive beyond 5 years.[1] While surviving cancer treatment, prostate cancer survivors may experience long-term treatment side effects (e.g., incontinence, sexual dysfunction) that challenge the patient’s sense of masculinity and identity,[2-4] impact upon life satisfaction, and reduce mental and social well-being.[5,6] - Published in 2015
Who decides about prostate cancer treatment? A qualitative study
Academia
Shared decision-making between patients and health professionals has been promoted as ethically and clinically desirable. Patients vary in their willingness to participate in decision-making, while clinicians identify practical barriers to greater participation, such as time and communication skills. A paternalistic approach to treatment decisions remains common even in an area of clinical uncertainty. - Published in 2003
Treatment decision-making process of men with newly diagnosed localized prostate cancer: the role of multidisciplinary approach in patient engagement
Academia
The diagnosis of prostate cancer (PCa) often represents a stressful event. In addition to the psychological distress related to the diagnosis, patients face challenging health decisions: in fact, besides radical treatments, Active Surveillance may represent an option for patients with diagnosis of localized PCa. A multidisciplinary clinical approach seems to represent the suitable organizational model to meet such a requirement, optimizing the therapeutic outcome for PCa patients. The present study is a qualitative examination of the treatment decision-making process of men with a newly diagnosed localized PCa who received a multidisciplinary clinical consultation. - Published in 2019
Satisfaction with Information Used to Choose Prostate Cancer Treatment
Academia
After being diagnosed with prostate cancer men must assimilate information regarding the cancer. Satisfaction with information reflects the evaluation of information sources used before treatment to select a therapy. We describe the use and helpfulness of several information sources available to prostate cancer survivors. We also identified factors associated with satisfaction with information. - Published in 2014
Treatment Decision-making for Early Prostate Cancer Patients – What Can Nurses Do
Academia
This review investigates the topic of treatment decision-making for early prostate cancer patients. The research question to be addressed is "What can oncology nurses do to support men with early prostate cancer in making treatment decisions?" - Published in 2014
Communication: The key to improving the prostate cancer patient experience
Academia
Communication is defined as “to make known, to exchange information or opinions” (Cayne, Lechner, et al., 1988). Nursing is the critical link for information exchange that is patient-centred and collaborative. The focus of this paper will highlight the development and implementation of nurse-led initiatives within our program to improve the prostate cancer patient experience. - Published in 2012
Understanding Medical Decision-making in Prostate Cancer Care
Academia
The availability of several treatment options for prostate cancer creates a situation where patients may need to come to a shared decision with their health-care team regarding their care. Shared decision-making (SDM) is the concept of a patient and a health-care professional collaborating to make decisions about the patient’s treatment course. Nurse navigators (NNs) are health-care professionals often involved in the SDM process. The current project sought to evaluate the way in which patients with prostate cancer make decisions regarding their care and to determine patients’ perspectives of the role of the NN in the SDM process. - Published in 2018
Communicating with prostate cancer patients: Psychosocial profile and determinants of seeking psychosocial care
Academia
Prostate cancer patients often express needs for supportive care, even though they are not frequently participating in supportive care activities. We studied the psychosocial care needs in relation with the intention seeking psychosocial care in order to improve the communication with the prostate cancer patients about the best fitting psychosocial care. - Published in 2015
Men with prostate cancer and the accessibility to information—a literature review
Academia
A literature survey was carried out to get an insight in possible consequences by summarizing the state of knowledge on how men with prostate cancer undergoing prostatectomy surgery experience their contacts with the healthcare professionals. Results: A consequence is that often men with prostate cancer, treated with prostatectomy surgery, do not receive the individualized support, information, and dialogue they need, which leads to feelings of uncertainty, insecurity, and loss of control. The men use the Internet in their search for information and support, which makes them able to stay in control and be active, responsible partners in their own course of treatment. - Published in 2011
The information required by patients with early-stage prostate cancer in choosing their treatment
Academia
To determine the information that men diagnosed with early-stage prostate cancer think is necessary to choose their treatment (surgery, radiotherapy or `watchful waiting'). - Published in 2001
Treatment decision making in prostate cancer: Patients’ participation in complex decisions
Academia
(1) To explore to what degree prostate cancer (PC) patients felt they had participated in treatment decision making (TDM). (2) To determine whether perceived roles during TDM were associated with medical and sociodemographic variables. (3) To examine to what extent satisfaction with TDM was related to perceived role or medical and sociodemographic variables. - Published in 2006
Information for Decision Making by Patients With Early-Stage Prostate Cancer: A Comparison Across 9 Countries
Academia
To describe decisional roles of patients with early-stage prostate cancer in 9 countries and to compare the information they rated important for decision making (DM). - Published in 2011
Information needs of early-stage prostate cancer patients: A comparison of nine countries
Academia
Prostate cancer is the fifth most common cancer world-wide with large increases in its incidence in the last 25 years. With the advent of Prostate Specific Antigen (PSA) screening, in particular, the majority of the newly diagnosed cases have early-stage disease. Thus, ensuring that patients with early-stage prostate cancer feel informed would benefit a substantial and increasing proportion of men with cancer world-wide. - Published in 2010
Men with prostate cancer: influence of psychological factors on informational needs and decision making
Academia
Studies indicate that men with prostate cancer (MPC) adopt passive roles in cancer management; however, increasing public awareness of prostate cancer and advocacy by MPC and their allies suggest otherwise. This study looks at the information that is important to MPC; their preferred participation in decision making; and the influence of sociodemographic, disease, and psychological factors on information needs and decision preferences. - Published in 2000
Improving fitness may be linked to a 35% lower risk of prostate cancer, study finds
NBC News
Plenty of research has linked regular exercise to a lower risk of cancer, but a new study suggests that getting into better shape could reduce the risk of prostate cancer in particular, a diagnosis that around 113 out of every 100,000 men get every year in the U.S.
Prostate Cancer Support Toronto Videos
Prostate Cancer Support Toronto
Prostate Cancer Support Toronto Awareness Night Videos with experts in cancer research, psychology, and physiotherapists",
Video,Learn Here,Treatment,Radiation Therapy,Sunnybrook Cancer Centre ,https://sunnybrook.ca/content/?page=prostate-cancer-brachytherapy%20,Prostate Brachytherapy: What to Expect,,"Brachytherapy involves the temporary placement of radioactive seeds into the prostate. This video explains what will happen you go through this treatment."
Blood Test may be 94% Effective at Spotting Prostate Cancer
National Post
With the current PSA screening test has shown to be inaccurate, the preliminary findings of a new blood test show promise as a screening tool for prostate cancer. *Published February 2023
Study Co-Authored by Niagara Health Doctor Increases Treatment Options for Prostate Cancer Patients
Niagara Health
Researchers from Niagara Health have found that prostate cancer patients whose cancer returns after being treated with high-intensity focused ultrasound (HiFU) therapy can safely receive higher doses of radiation therapy. *Published October 2022
Phase 3 Study Shows XTANDI® (Enzalutamide) plus Leuprolide Significantly Improves Metastasis-Free Survival in Men with Nonmetastatic Prostate Cancer
Newswire
This Phase 3 clinical trial has shown significant improvements in metastasis-free survival for men with non-metastatic hormone (or castration) -sensitive prostate cancer and those at high risk for biochemical recurrence. *Published March 2023
Early diagnosis of prostate cancer: which test is best?
Population Data BC
A new screening method for prostate cancer is being trialled in British Columbia based on a blood test. *Published July 2022
Prostate Cancer News
Science Daily
Stay up to date with all the latest prostate cancer news using this webpage.
Exosome Diagnostics Releases Interim Results From Clinical Study of Prostate Cancer Risk Test
StockHouse
Typical prostate cancer screening tests distinguish between low-risk and high-risk cases; however, most patients fall in the middle. Researchers hope the current study will provide more in-depth information to guide health decisions for prostate cancer diagnosis. *Published May 2023
Personalization May Improve Prostate Cancer Screening Accuracy
Technology Networks
This recent study has taken a significant step in the right direction for prostate cancer screening! By examining the personalized genetic makeup of patients, researchers were able to determine gene variations in PSA levels unrelated to cancer, cutting down on unnecessary biopsies and improving the diagnosis of aggressive tumours. *Published June 2023
Understanding the Key Facts and Figures about Prostate Cancer Research.
The Terry Fox Research Insitute
The Terry Fox Research Institute has embarked on a multi-pronged strategy to fund the country's best prostate cancer scientific teams and programs.
Artificial Intelligence may Enhance the Efficacy of mpMRI in Prostate Cancer.
Urology Times
Multiparametric MRI is a promising diagnostic tool for prostate cancer that may reduce the need for biopsies to confirm the disease however, lesions can be difficult to detect. This study demonstrates the effectiveness of AI software at increasing the sensititvity for detection of prostate cancer. *Published May 2023
Bone Biomarkers Found to be Prognostic for Overall Survival in Prostate Cancer
Urology times
Bone biomarkers have previously been implicated in castration-resistant prostate cancer. This new study found that these biomarkers may also benefit the understanding of hormone-sensitive prostate cancer. Lower serum levels of these bone metabolism markers were associated with a lower mortality risk. *Published May 2023
Dr. Arenas-Gallo highlights findings on DNA alteration frequency in Hispanic men with prostate cancer
Urology times
This study examined the genetics of Hispanic men with prostate cancer and found they show important alterations in genes related to prostate cancer compared to non-Hispanic men. This is an essential step towards creating targeted therapies for individuals. *Published May 2023
Dr. Ryan on expanding benefits of PSMA-PET imaging in prostate cancer
Urology times
PSMA-PET scans are gaining a foot hold in emerging technologies for the diagnosis of prostate cancer. For patients with high-risk localized prostate cancer this imaging technique may provide physicians with a better indication as to what treatment route to use. Listen to Dr.Ryan explain the benefits of PSMA-PET imaging. *Published May 2023
Diseases and Physical Health Conditions – Cancer
Statistics Canada
This database allows you to view recent trends in cancer prevalence. Searches can be filtered by cancer type for specific results however general overviews are available as well.
Journal of the National Cancer Institute
Oxford Academic
This resource provides current articles relevant to prostate cancer research and practices.
Dalhousie University on the Benefits of PC-PEP
Dalhousie University
According to a study of Nova Scotian men, a new program to help cancer patients and survivors take charge of their physical and mental health after prostate cancer treatment has dramatically reduced psychological distress.
Prostate Cancer Risk Calculator for MRI-guided biopsy (PCRC-MRI)
Alberta Prostate Cancer Research Initiative
A new tool from the University of Alberta, in collaboration with UCLA, helps to reduce unnecessary prostate biopsies and target people based on the probable outcome of a biopsy. *Published February 2022
Study Reveals Serious Cancer Research Gaps for Black Canadians
CBC
In a new study, the University of Ottawa's Interdisciplinary Centre for Black Health (ICBH) has discovered "large gaps in research" on how common types of cancer affect Black people in Canada. After conducting a meta-analysis of medical literature and the 20 most common types of cancer in Canada, the researchers behind the study found no data related to Black people. "What we found is … a real gap when we compared [cancer] research within Black communities and research within other communities," said Jude Mary Cénat, an associate professor at the university's School of psychology and ICBH director. *Published February 2023
Search of: Prostate Cancer
Clinical Trials
This database provides the most up-to-date information on current clinical trials, including those actively recruiting. Filters can be set for cancer type, eligibility criteria, study type, phase, and location
Role of Enzyme in Prostate Cancer Development Discovered; Shows Promise in Tackling Resistance to Treatment
international Business Times
New research has identified an enzyme involved in prostate cancer metabolism and the development of treatment resistance. Targetting this enzyme shows promise as a novel therapy for treatment-resistant prostate cancer. *Published February 2023
Chronic Hypoxia Favours Adoption to a Castration-Resistant Cell State in Prostate cancer.
Institute for Research in Immunology and Cancer
This publication provides the latest discovery for possible hypoxic prostate cancer treatment. Despite identifying genomic instability and hypoxia as risk factors, predicting and treating recurrence in intermediate-risk prostate cancer patients remains challenging. This underlies challenges in assigning the functional impact of these risk factors to mechanisms promoting prostate cancer progression. *Published April 2023